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KMID : 1001920080430040194
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Journal of Korean Neurosurgical Society
2008 Volume.43 No. 4 p.194 ~ p.197
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Cerebellar Glioblastoma Multiforme in an Adult
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Hur Hyuk
Jeong Shin-Young
Jung Tae-Young
Kim In-Young
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Abstract
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Primary cerebellar glioblastoma multiforme (GBM) is a rare tumor in adults that accounts for just 1% of all cases of GBM. Due to their rarity, cerebellar GBMs are not yet completely understood about the pathogenesis and the prognosis. Here, we present a case of GBM in a 69-year-old man. Neurologic examination revealed the presence of cerebellar signs. Magnetic resonance imaging (MRI) showed a 4.5 x 3.6 cm-sized, ill-defined, heterogeneously enhancing mass in the left cerebellum and two patchy hyperintense lesions in the right cerebellum with minimal enhancement. After operation, glioblastoma was histologically confirmed. Postoperative radiotherapy with concomitant and adjuvant temozolomide chemotherapy was subsequently followed. Here, a case of unusual GBM in the cerebellum is reported with review of literature regarding the pathogenesis, the differential diagnosis and prognosis. There was no evidence of recurrence during postoperative one year. This patient showed a good prognosis in spite of the multiple lesions.
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KEYWORD
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Cerebellum, Differential diagnosis, Glioblastoma multiforme, Pathogenesis
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